Adjunct Professor, Food, Nutrition & Health
FNH Building
2205 East Mall
Vancouver, BC V6T 1Z4
Canada

Education

University of Salford, Manchester, PhD, Pharmaceutical Organic Chemistry
University of Salford, Manchester, BSc (Hons), Applied Chemistry

Research

Developing science on natural products from structural identification through preclinical studies to human trials at CRO’s and Universities around the world and then using these to attain status with regulators globally.  Other interest involves combining natural products with Pharmaceutical products.

Selected Publications

Yong MK, Solah VA, Johnson SK, Meng X, Kerr DA, James AP, Fenton HK, Gahler RJ, Wood S. Effects of a viscous-fibre supplemented evening meal and the following un-supplemented breakfast on post-prandial satiety responses in healthy women. Physiology & Behavior. 2016; doi:10.1016/j.physbeh.2015.11.006

Reimer RA, Grover GJ, Koetzner L, Gahler RJ, Lyon MR, Wood S. Combining sitagliptin/metformin with a functional fiber delays diabetes progression in Zucker rats. J Endocrinol. 2014; doi:10.1530/JOE-13-0484

Smith IH, Lawson CJ, Harding SE, Gahler RJ, Lyon MR, Wood S. Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides. Food Hydrocolloids. 2014;doi: 10.1016/ j.foodhyd.2013.12.004

Beer C, Wood S, Veghte RH. A randomized, double-blind, placebo-controlled clinical trial to investigate the effect of Cynatine® FLX on symptoms of osteoarthritis. J Diet Suppl. 2013; doi:10.3109/19390211.2013.822449

Reimer RA, Yamaguchi H, Eller LK, Lyon MR, Gahler RJ, Kacinik V, Juneja P, Wood S. Changes in visceral adiposity and serum cholesterol with a novel viscous polysaccharide in Japanese adults with abdominal obesity. Obesity. 2013;doi:10.1002/oby.20435

Reichert RG, Lyon MR, Kacinik V, Gahler RJ, Manjoo P, Purnama M, Wood S. Decreasing cardiovascular risk factors in obese individuals using a combination of PGX® meal replacements and PGX® granules in a 12-week clinical weight modification program. J Complement Integr Med. 2013;10:1–8

Reichert RG, Reimer RA, Kacinik V, Pal S, Gahler RJ, Wood S. Meal replacements and fibre supplement as a strategy for weightloss. Proprietary PGX® meal replacement and PGX® fibre supplement in addition to a calorie-restricted diet to achieve weight loss in a clinical setting. Biotechnol Genet Eng. 2013;doi:10.1080/02648725.2013.801229

Beer C, Wood S, Veghte RH. A randomized, double-blind, placebo-controlled clinical trial to investigate the effect of Cynatine® HNS on skin characteristics. Int J Cosmet Sci. 2013;doi: 10.1111/ics.12084.

Reimer RA, Grover GJ, Koetzner L, Gahler RJ, Juneja P, Lyon MR, Wood S. Sitagliptin reduces hyperglycemia and increases satiety hormone secretion more effectively when used with a novel polysaccharide in obese zucker rats. J Nutr. 2012;142:1812-20

Methanolysis of 6-hydroxy-7-methyl-6-phenylandamantane-2,4-dione.  P W Hickmott and S Wood, S. Afr. J. Chem., 1985, 38, 17

Introduction of pharmacophoric groups into polycyclic systems.   Part 2.  Adamantane derivatives of 3-methylene-2-oxofuran.  P W Hickmott and S Wood,  S. Afr. J. Chem., 1985, 38, 61

Reactions of unsaturated acid chlorides with 4,4-disubstituted cyclohexanone enamines.  S A Ahmed, P W  Hickmott and S Wood, S Afr. J. Chem., 1985, 38, 54

Amine derivatives of adamantane and diazaadamantane.  P W Hickmott, P Murray-Rust and S Wood, J.C.S., Perkin I, 1985, 2033.

Preparation of substituted adamantane-2,4-diones and ethyl-4,6-dioxoadamantane-1-carboxylate from ab-unsaturated acid chlorides and 4,4-disubstituted cyclohexanone enamines.  Stereochemistry and mechanism of formation.  M G Ahmed, S A Ahmed, P W Hickmott, M Kapon and S Wood, J.C.S. Perkin I , 1985, 2559.

Comparison of new 99mTc adamantane-ida compounds with 99mTc bat brain agents.  A J Van Wyk, P J Fourie, P Bekker, S Wood, K A Smith, I Gerber and J du Preez.  Presented at the 4th international symposium on radiopharmachology, Canada, 1985 and published in the proceedings, March 1986

A rapid method for the determination of propanolol in plasma. K A Smith, S Wood and G M Crous.  The Analyst, 1987, 112, 407.

Matulka RA, Lyon MR, Wood S, Marone PA, Merkel DJ, Burdock GA. The safety of PolyGlycopleX® (PGX®) as shown in a 90-day rodent feeding study. Nutr J. 2009;8:1.

Marone PA, Lyon MR, Gahler R, Donath C, Hofman-Hüther H, Wood S. Genotoxicity studies of PolyGlycopleX®(PGX®): A novel Dietary Fiber. Int J Toxicol. 2009;28:318-331.

Carabin IG, Lyon MR, Wood S, Pelletier X, Donazzolo Y, Burdock GA. Supplementation of the diet with the functional fiber PolyGlycopleX® is well tolerated by healthy subjects in a clinical trial. Nutr J. 2009:8:9.

Reimer RA, Pelletier X, Carabin IG, Lyon M, Gahler R, Parnell JA, Wood S. Increased plasma PYY levels following supplementation with the functional fiber PolyGlycopleX in healthy adults. Eur J Clin Nutr. 2010;64:1186-1191.

Miller-Brand JC, Atkinson FS, Gahler RJ, Kacinik V, Lyon MR, Wood S. Effects of PGX, a novel functional fibre, on acute and delayed postprandial glycaemia. Eur J Clin Nutr. 2010;64:1488-1493

Correlating Preclinical, Clinical and Post Marketing Surveillance Data: A Case Study.  Carabin, Roland Gahler, Michael Lyon, Simon Wood, Terra Brown, Veronica Kacinik, George Burdock, Nutraceutical, Vol 6, # 5, 2010, 12-17,

Abdelhameed AS, Ang S, Morris GA, Smith I, Lawson C, Gahler R, Wood S, Harding SE. An analytical ultracentrifuge study on ternary mixtures of konjac glucomannan supplemented with sodium alginate and xanthan gum. Carbohyd Polym. 2010:81;145-148.

Increased plasma PYY levels following  supplementation with the functional fiber PolyGlycopleX in healthy adults.  RA Reimer, X Pelletier, IG Carabin, M Lyon, R Gahler, JA Parnell and S Wood.  European Journal of Clinical Nutrition (2010), 1–6

Harding SE, Smith IH, Lawson CJ, Gahler R, Wood S. Studies on macromolecular interactions in ternary mixtures of konjac glucomannan, xanthan gum and sodium alginate. Carbohyd Polym. 2011;83:329-338.

Effects of a 3-month supplementation with a soluble viscous polysaccharide on anthropometry and blood lipids in non-dieting overweight or obese adults. Lyon M., Wood S, Pelletier X, Donnazzolo Y.,Gahler R., Bellisle F.  JHND, 2011, doi:10.1111/j.1365-277X.2011.01157

The Soluble Fibre Complex PolyGlycopleX® (PGX®) Attenuates Weight Gain and Lowers Serum Triglycerides in Sucrose-Fed Rats   Raylene A Reimer;  Gary J Grover; Lee Koetzner; Roland J Gahler; Michael R Lyon; Simon Wood.  Nut. Res, 31 (2011), 296-301

Faecal short chain fatty acids in healthy subjects participating in a randomised controlled trial examining a soluble highly viscous polysaccharide versus control.  Reimer R.A., Pelletier X.,Carabin I.G., Lyon M, R., Gahler R, and Wood S     Journal of Human Nutrition and Dietetics  doi:10.1111/j.1365-277X.2012.01230.x

Effects of the soluble fiber complex PolyGlycopleX® on glucosehomeostasis and bodyweight inyoung Zucker diabetic rats Gary J. Grover, Lee Koetzner, Joan Wicks, Roland J.Gahler, Michael R.Lyon, Raylene A. Reimer, Simon Wood.   Frontiers in Pharmacology | Pharmacology of Natural Products,  September 2011 | Volume2 | Article47|1

Grover GJ, Koetzner L, Wicks J, Gahler RJ, Lyon MR, Reimer RA, Wood S. Effects of the soluble fiber complex PolyGlycopleX® (PGX®) on glycemic control, insulin secretion, and GLP-1 levels in Zucker diabetic rats. Life Sci. 2011;88:392-399.

Effects of added PGX®, a novel functional fibre, on the glycaemic index of starchy foods.  Jennie C. Brand-Miller PhD, Fiona S. Atkinson  MNutrDiet, Roland J. Gahler,  Veronica Kacinik MSc, RD, Michael R. Lyon MD, Simon Wood PhD.  Br Nut J. doi:10.1017/S0007114511005447

Effect of PGX, a novel functional fibre supplement, on subjective ratings of appetite in overweight and obese women consuming a 3-day structured, low-calorie diet.  V Kacinik, M Lyon, M Purnama, RA Reimer, R Gahler, TJ Green and S Wood.  Nutrition and Diabetes (2011) 1, e22; doi:10.1038/nutd.2011.18

Toxicologic evaluation of a plant food concentrate.  Palma Ann Marone, Mark Bauter, Hana Hofman-Hüther, Roland J. Gahler and Simon Wood.  International Journal of Nutrition and Metabolism Vol. 3(11), pp. 136-139, December 2011

Toxicological evaluation of oregano oil .  Palma Ann Marone, Mark Bauter, Hana Hofman-Huether, Roland J. Gahler and Simon Wood.  International Journal of Nutrition and Metabolism Vol. 4(6), pp. 83-89, June 2012

Dilute Solution Viscometry Studies on a Therapeutic Mixture of  Non-digestible Carbohydrates.   Stephen E. Harding, Fahad Almutairi, Gary G. Adams, Gordon Morris,  Christopher J. Lawson, Roland J. Gahler and Simon Wood.  International Journal of Biotechnology for Wellness Industries, 2012, 1107-114

Reichert RG, Lyon MR, Kacinik V, Gahler RJ, Manjoo P, Purnama M, Wood S. Decreasing cardiovascular risk factors in obese individuals using a combination of PGX® meal replacements and PGX® granules in a 12-week clinical weight modification program. J Complement Integr Med. 2013;10:1-8.