Beryl March

Born and raised in Vancouver, George Kennedy first experienced agriculture on his grandparent’s dairy farm in the Fraser Valley. After high school, he took general arts and science courses at UBC and earned a BA in Psychology and Sociology in 1968. He then spent a summer establishing an alfalfa field on his family’s farm in the Okanagan Valley. This experience convinced him to pursue a career in agriculture. He began with a year of course work at the University of Guelph, then to the University of Minnesota for an MSc (1970), and to Purdue University for a PhD (1973), all in agricultural economics.

In 1974, Dr Kennedy began working for Agriculture Canada as a research economist for two years before joining the Department of Agricultural Economics at UBC as an Assistant Professor in 1976. He was promoted to Associate Professor in 1985. His teaching and research have spanned a number of areas, from farm management to agricultural policy. His research interests have increasingly focused on international development. He spent 1982-83 researching economic development in Japan as a Visiting Scholar at Kobe University. In 1988, he spent six months in Nepal as the economist on an IDRC sponsored watershed study.

In 1991, Dr Kennedy was appointed Director of International Programs in the Faculty of Agricultural Sciences. Under Kennedy’s leadership, the Faculty has become one of the most internationally active at UBC. He spent 1993-94 on sabbatical at Lincoln University, New Zealand. On returning to UBC, he was named Head of the Department of Agricultural Economics for the period 1994-1996. Kennedy continues to serve as Director of Global Partnerships (formerly International Programs) for the Faculty of Agricultural Sciences. He is also Academic Coordinator for the Faculty’s Global Resource Systems Undergraduate program.

As Director of the Faculty’s Global Partnerships, Dr Kennedy was instrumental in UBC’s becoming a member of the South East Asian University Consortium for Graduate Education in Agriculture and Natural Resources; in the Tokyo University of Agriculture exchanges; in the Faculty’s participation in the Student Exchange Program; and in other initiatives involving international education. In 2002, he won the Scotiabank-AUCC (Association of Universities and Colleges in Canada) Award for Excellence in Internationalization for the Global Resource Systems Program in the category “Broadening the Student Experience.”

Dr Kennedy has received research funding from a number of local, national and international agencies. He has presented papers on topics such as Interdisciplinary Teaching, International Agri-Food Trade Patterns and Sustainable Agriculture at a number of international conferences. He has also published papers in several Canadian and international journals dealing with agricultural economics and international development.

In 2010, George helped launch the Master of Food and Resource Economics program, the first professional masters degree in Canada to offer a combination of applied economics, policy analysis and agribusiness management. George serves as Academic Advisor and Manager for the MFRE program.

R Blair and C R Nichols 2002

After taking a leave of absence in September 2010 to concentrate full-time on EnWave , a local research and development company that he co-founded, Tim Durance officially stepped down from his role as Professor, Food, Nutrition and Health in 2012.

Professor Emeritus Durance joined the Faculty as an Assistant Professor in 1987. In 2002, he was promoted to Professor and Program Director, FNH, a position he held for four years.

It was in his lab at UBC that the technology for EnWave’s radiant energy vacuum (REV) was developed. NutraREV uses vacuum pressure and microwave energy to deliver rapid, low-temperature dehydration of fruits, vegetables and other food materials, while preserving vitamins and nutrients.

Tim is the author of more than 75 peer-reviewed scientific publications, 16 patents, and numerous book chapters, scientific presentations, and invited lectures on technology and food processing. He received his Ph.D and M.Sc. in Food Science from UBC, as well as a B.Sc. in Microbiology from the University of Guelph and a B.A. in Anthropology from the University of Waterloo.

In 2012, Tim received the Investment Agriculture Foundation of B.C.’s Award of Excellence for Innovation in Agriculture and AgriFood, an award that celebrates innovative thinkers who help drive B.C.’s agriculture and agri-food industry forward. He also received the Life Sciences British Columbia Innovation and Achievement award in the same year.

J. Honeybourn, 2013

After a long and distinguished career, Associate Professor Art Bomke retired in July 2011. A favourite among students, Bomke received the UBC Killam Teaching Prize award twice (1999 and 2010), a rare honour.

Bomke was hired by UBC as an Assistant Professor in 1973 after completing his PhD at the University of Illinois. In 1990, he was promoted to Associate Professor, subsequently serving as Acting Head of the former Department of Soil Science and eventually became Director of the Agroecology program (now the Applied Biology program) in the early 2000s.

An athlete, Bomke is a two-time silver medallist in basketball, competing in 2005 and 2009 at the World Masters Games. He biked to work for years and it was while riding his bike in 2008 that he and a friend discovered apple trees on campus that are directly descended from the apples that inspired Newton to compose his theory of gravity in 1661.

Bomke has a real connection to the land and farmers. A strong proponent of small-scale agriculture, he helped resurrect UBC farm and has a hand in where the UBC Farm is at today. He was also involved with the development of the Orchard Garden, which, like UBC Farm, serves as an outdoor classroom for hands-on learning about small-scale urban farming and sustainable practices.

J. Honeybourn, 2012

State University of Ghent, Ph.D, Microbiology

University of Stellenbosch, MSc, Microbiology

University of Stellenbosch, BSc, Honours Microbiology

Dr. van Vuuren is a pioneer in the field of metabolic enhancement of wine yeasts. The first two genetically engineered wine yeasts to receive Generally Regarded As Safe (GRAS) status from the US FDA were constructed in his laboratory. The malolactic wine yeast, ML01, degrades malic acid to lactic acid during the alcoholic fermentation, prevents spoilage of wines by other microorganisms and prevents or limits the formation of bioamines (allergens) in wines. S. cerevisiae ML01 is both the first genetically enhanced wine yeast to receive GRAS status from the US FDA and to be commercialized by the wine industry. Notifications have been submitted to regulatory bodies in other wine producing countries to obtain permission for commercialization of ML01.

Novel urea-degrading wine yeasts that will significantly limit the formation of ethyl carbamate (urethane) in wines and brandy have recently been engineered in Dr. van Vuuren’s laboratory.

This naturally occurring compound can be found in many fermented foods and beverages. Ethyl carbamate is considered potentially dangerous to humans, as it exhibits carcinogenic activity in a variety of laboratory animals. Ethyl carbamate is genotoxic in vitro and in vivo. In 2004, the NTP released a report based on an extensive study and found that ethyl carbamate increased the rates of cancer of the liver, lung, harderian gland, and of hemangiosarcomas in both female and male mice. Ethyl carbamate also increased the rates of cancer of the mammary gland and ovaries in female mice and the rates of skin cancer and cancer of the forestomach in male mice. The urea-degrading red wine yeast developed in his laboratory has also received FDA GRAS status (link) and is currently being commercialized.

Fundamental research in the van Vuuren laboratory focuses on the metabolic adaptation of wine yeast to stresses during wine fermentation. A systems biology approach (transcriptomics, proteomics and metabolomics) is used to study how yeast cells adapt to nutrient depletion, increasing ethanol concentration and fermentation stress in general. The function of a number of orphan genes expressed only during the late stages of alcoholic fermentation in S. cerevisiae, is being elucidated.

Professor van Vuuren is currently Scientific Director of Creatus Biosciences Inc. in Vancouver.

Zara, H.J.J. van Vuuren, I. Mannazzu, S. Zara and M. Budroni. 2019. Transcriptional response of Saccharomyces cerevisiae during fermentation under oleic acid and ergosterol depletion. Fermentation 5: 57 https://www.mdpi.com/2311-5637/5/3/57?type=check_update&version=1

Bejaei, M.A. Cliff, L.L. Madilao and H.J.J. van Vuuren. 2019. Modelling changes in volatile compounds in British Columbian varietal wines that were bottle aged for up to 120 months. Beverages. 5, 57 https://open.library.ubc.ca/cIRcle/collections/facultyresearchandpublications/52383/items/1.0380946

Luo, H.J.J. van Vuuren, A.G. DeBono and A.T. Ferguson. 2019. Xylitol producing Metschnikowia species.  US Patent 10,435,721 B2. October 8, 2019.

Roach MJ, Johnson DL, Bohlmann J, van Vuuren HJJ, Jones SJM, Pretorius IS, et al. (2018) Population sequencing reveals clonal diversity and ancestral inbreeding in the grapevine cultivar Chardonnay. PLoS Genet 14(11): e1007807.

Terrell, E., M.A. Cliff  and H.J. J. van Vuuren. 2015. Functional Characterization of Individual- and Mixed-Burgundian Saccharomyces cerevisiae Isolates for Fermentation of Pinot Noir. Molecules. Molecules 20:3 5112-5136.

Walkey, C.J., D.D. Kitts, Y. Liu and H.J.J. van Vuuren. 2015. Bioengineering yeast to enhance folate levels in wine. Process Biochem. 50:205–210.

Saberi, S., M. Cliff and H.J.J. van Vuuren. Comparison of Genetic and Enological Characteristics of New and Existing S. cerevisiae Strains for Chardonnay Wine Fermentations. Food Biotech. 28:195–215.

Bessonov, K., C.J. Walkey, B.J. Shelp, H.J.J. van Vuuren, D. Chiu and G. van der Merwe. 2013. Functional analyses of NSF1 in wine yeast using interconnected correlation clustering and molecular analyses. PLoS One. Oct 9;8(10):e77192. doi: 10.1371/journal.pone.0077192.

Luo, Z., C.J. Walkey, L.L. Madilao, V. Measday and H.J.J. van Vuuren. 2013. Functional improvement of Saccharomyces cerevisiae to reduce volatile acidity in wine. FEMS Yeast 13(5):485-94.

Walkey, C.J., Z. Luo, L.L. Madilao and H.J.J. van Vuuren. 2012. The Fermentation Stress Response Protein Aaf1p/Yml081Wp Regulates Acetate Production in Saccharomyces cerevisiae. PLoS ONE 7(12):e51551.

Saberi, S., M.A. Cliff and H.J.J. van Vuuren. 2012. Impact of mixed S. cerevisiae strains on the production of volatiles and estimated sensory profiles of Chardonnay wines. Food Res. Internat. 48:725-735.

Walkey, C.J., Z. Luo, C.H. Borchers, V. Measday and H.J.J. van Vuuren. 2011. The Saccharomyces cerevisiae fermentation stress response protein Igd1p/Yfr017p regulates glycogen levels by inhibiting glycogen debranching enzyme. FEMS Yeast Res. 11:499-508.

Deed, N.K., H.J.J. van Vuuren and R.C. Gardner. 2011. Effects of nitrogen catabolite repression and di-ammonium phosphate addition during wine fermentation by a commercial strain of S. cerevisiae. Appl. Microbiol. Biotechnol. 89:1537-1549.

Dahabieh, M., J. I. Husnik and H.J.J. van Vuuren. 2010. Functional enhancement of Sake yeast strains to minimize the production of ethyl carbamate in Sake wine. J. Appl. Microbiol. 109:963-973.

Adams, C. and H.J.J. van Vuuren. 2010. The timing of diammonium phosphate addition to fermenting grape must affects the production of ethyl carbamate in wine. Am. J. Enol. Vitic. 61:125-129.

Dahabieh, M. and H.J.J. van Vuuren. 2009. Functional expression of the DUR3 gene in a wine yeast strain to minimize ethyl carbamate in Chardonnay wine. Am. J. Enol. Vitic. 60:537-541.

Luo, Z. and H. J. J. van Vuuren. 2009. Functional analyses of PAU genes in Saccharomyces cerevisiae. Microbiology 155:4036-4049.

Erasmus D. J. and H.J.J. van Vuuren. 2009. Genetic Basis for Osmosensitivity and Genetic Instability of the Wine Yeast Saccharomyces cerevisiae VIN7. Am. J. Enol. Vitic. 60:145-154.

Lou, Z. and H.J.J. van Vuuren. 2008. Stress-induced production, processing and stability of a seripauperin protein, Pau5p, in Saccharomyces cerevisiae. FEMS Yeast Res. 8:374-385.

Van Vuuren, H.J.J., J.I. Husnik and C. Adams. 2008. Metabolically enhanced yeasts that conduct the malolactic fermentation and limit ethyl carbamate in wine. Proceedings of the Australian Wine Industry Technical Conference. 2008:171-177.

Marks, V.D., S.J. Ho Sui, D. Erasmus, G.K. van der Merwe, J. Brumm, W.W. Wasserman, J. Bryan and H. J. J. van Vuuren. 2008. Dynamics of the yeast transcriptome during wine fermentation reveals the Fermentation Stress Response. FEMS Yeast Res. 8:35-52.

• Supplementary data, Marks et al. 2008

Volschenk, H., H.J.J. van Vuuren & M. Viljoen-Bloom. 2006. Malic Acid in Wine: Origin, Function and Metabolism during Vinification. S. Afr. J. Enol. Vitic. 27(2) 123-136.

Coulon, J., J. I. Husnik, D. L. Inglis, G. K. van der Merwe, A. Lonvaud, D. J. Erasmus and H. J.J. van Vuuren. 2006. Metabolic Engineering of Saccharomyces cerevisiae to minimize the production of ethyl carbamate in wine. Am. J. Enol. Vitic. 57:113-24.

Husnik, J.I., H. Volschenk, J. Bauer, D. Colavizza, Z. Luo, Z. and H. J. J. van Vuuren, 2006. Metabolic engineering of malolactic wine yeast. Metabolic Eng. 8:315-323.

Greatrix, B. W. and H.J.J. van Vuuren. 2006. Expression of the HXT17, HXT13 and HXT15 genes in Saccharomyces cerevisiae; stabilization of the HXT1, GPD1 and HTB1 gene transcripts by sugar-induced osmotic stress. Curr. Genetics. 49:205-217.

Van Staden, J., H. Volschenk, H.J.J. van Vuuren and M. Viljoen-Bloom. 2005. The Effect of Skin Contact on Malic Acid Degradation by Recombinant Malo-ethanolic Wine Yeast Strains. S. Afr. J. Enol. Vitic. 26:16-20.

Volschenk, H., M. Viljoen-Bloom, J. van Staden, J. Husnik and H.J.J. van Vuuren. 2004. Genetic engineering of an industrial strain of Saccharomyces cerevisiae for L-malic acid degradation via an efficient malo-ethanolic pathway. S. Afr. J. Enol. Vitic. 25:63-73.

Erasmus, D.J., M. Cliff and H.J.J. van Vuuren. 2004. Impact of yeast strain on the production of acetic acid, glycerol and the sensory attributes of icewine. Am. J. Enol. Vitic. 55:371-378.

Subden, R.E., J.I. Husnik, R. van Twest, G.K. van der Merwe and H.J.J. van Vuuren. 2003. Autochthonous microbial population in a Niagara Peninsula icewine must. Food Res. Int. 36:747-751.

Volshenk, H., H.J.J. van Vuuren and M. Viljoen-Bloom. 2003. Malo-ethanolic fermentation in Saccharomyces and Schizosaccharomyces. Curr. Genetics. 43: 379-391.

Erasmus, D.J., G.K. van der Merwe and H.J.J. van Vuuren. 2003. Genome-wide expression analyses: Metabolic adaptation of Saccharomyces cerevisiae to high sugar stress. FEMS Yeast Res. 3:375-399.

Marks, V., G.K. van der Merwe and H.J.J. van Vuuren. 2003. Transcriptional profiling of wine yeast in fermenting grape must: Regulatory effect of diammonium phosphate. FEMS Yeast Res. 3:269-287.

van der Merwe G.K., T.G. Cooper and H.J.J. van Vuuren. 2001. Ammonia regulates VID30 expression and Vid30p function shifts nitrogen metabolism towards glutamate formation especially when Saccharomyces cerevisiae is grown in low concentrations of ammonia. J. Biol. Chem. 276:28659-28666.

van der Merwe G.K., H.J.J. van Vuuren and T.G. Cooper. 2001. Cis-acting sites contributing to expression of divergently transcribed DAL1 and DAL4 genes in S. cerevisiae: a word of caution when correlating cis-acting sequences with genome-wide expression analyses. Curr. Genetics. 39:156-165.

Volschenk, H., M. Viljoen-Bloom, R.E. Subden and H.J.J. van Vuuren. 2001. Malo-ethanolic fermentation in grape must by recombinant strains of Saccharomyces cerevisiae. Yeast. 18:963-970.

Saayman, M., H. J. J. van Vuuren, W. H. van Zyl and M..Viljoen-Bloom. 2000. Differential uptake of fumarate by Candida utilis and Schizosaccharomyces pombe. Appl. Microbiol. Biotechnol. 54:792-798.

Viljoen M., H. Volschenk, R.A. Young and H.J.J. van Vuuren. 1999. Transcriptional regulation of the Schizosaccharomyces pombe malic enzyme gene, mae2. J. Biol. Chem. 272:9969-9975.

Subden, R.E., A. Krizus, C. Osothsilp, M. Viljoen and H.J.J. van Vuuren. 1998. Mutational analysis of malate pathways in Schizosaccharomyces pombe. Food Res. Int. 31:37-42.

Viljoen, M., M. van der Merwe, R.E. Subden and H.J.J. van Vuuren 1998. Mutation of Gly-444 Inactivates the S. pombe Malic Enzyme. FEMS Lett. 167:157-162.

Volschenk, H., M. Viljoen, J. Grobler, F. Bauer, R.E. Subden, A. Lonvaud, M. Denayrolles and H.J.J. van Vuuren. 1997. Malolactic fermentation in grape musts by a genetically engineered strain of Saccharomyces cerevisiae. Am. J. Enol. Vitic. 48:193-197.

Volschenk, H., M. Viljoen, J. Grobler, B. Petzold, F. Bauer, R.E. Subden, R.A. Young, A. Lonvaud, M. Denayrolles and H.J.J. van Vuuren. 1997. Engineering pathways for malate degradation in Saccharomyces cerevisiae. Nature Biotechnol. 15:253-257.

Liao, S.M., J. Zhang, D.A. Jeffery, A.J. Koleske, C.M. Thompson, M. Viljoen, H.J.J. van Vuuren and R.A. Young. 1995. A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature 374:193-196.

Grobler, J., F. Bauer, R.E. Subden and H.J.J. van Vuuren. 1995. The mae1 gene of Schizosaccharomyces pombe encodes a permease for malate and other C4 dicarboxylic acids. Yeast 11:1485-1491.

Sutherland, M.H., H.J.J. van Vuuren and M.M. Howe. 1994. Cloning, sequence and in vitro transcription/translation analysis of a 3.2-kb EcoRI-HindIII fragment of Leuconostoc oenos bacteriophage L10. Gene. 148:125-129.

Viljoen, M., R.E. Subden, A. Krizus & H.J.J. van Vuuren. 1994. Molecular analysis of the malic enzyme gene (mae2) of Schizosaccharomyces pombe. Yeast 10:613-624.

Before he immigrated to Canada, Dr. van Vuuren was head of the Department of Microbiology and Founding Director of the Institute for Biotechnology at Stellenbosch University in South Africa. In 1997 he was recruited as Professor and Senior NSERC/Industrial Research Chair in the Cool Climate Oenology and Viticulture Institute at Brock University. In 1999 he was appointed to The Blythe and Violet Eagles Chair in Food Biotechnology in the Faculty of Land and Food Systems at UBC. He was the Founding Director of the Wine Research Centre at UBC in 1999.

• South African Society for Enology and Viticulture: most outstanding contribution in the field of Enology, paper in Nature Biotechnology (1997)
• American Society for Enology and Viticulture: most outstanding contribution in the field of Enology, paper in the American Journal of Enology & Viticulture (1998)
• Canada Foundation for Innovation: award for innovation and research excellence (1999)
• Nominated by the Globe and Mail as one of six scientists in Canada to watch this year (2011)
• Recognized by the BC Provincial Government as “Leading Researcher for the Year of Science” (2011)

Professor van Vuuren was the Founding Director and served as Director of the Wine Research Centre (WRC) from 1999-2016. He was Associate Dean Research and member of the Core Team for the Faculty of LFS from 2003-2012. He served on the UBC Senate and UBC Senate Admissions Committee during 2003-2004 and the VPR Committee of Associate Deans Research 2007- 2012. Professor van Vuuren also served as a member of the UBC Senate Senior Appointments Committee 2015-2017. He raised $14,8 million in research funding and funded renovation of two of the three research laboratories, he established the Core UBC Microarray facility, established the Core Mass Spectrometry Laboratory in the WRC along with Professor Joerg Bohlmann and established the UBC Wine Library in 2001.

Distinguished Visitors to Professor van Vuuren’s laboratory and the UBC Wine Library: 2001-2017

Nobel Laureates

Dr. Randy Sheckman, University of California, Berkeley and Howard Hughes Medical Institute

Dr. Paul Nurse, Director and Chief Executive, Francis Crick Institute, London UK

Dr. Sydney Brenner, Salk Institute La Jolla, USA

Dr. John Sulston, University of Manchester, UK

Other important visitors

Dr. Gerald Fink, MIT

Dr. Mike Snyder, Yale

Dr. David Botstein, Princeton

Dr. Jim Broach, Princeton

Dr. Denis Dubourdieu, University of Bordeaux, Owner Doisy-Daëne and Barsac

Dr. Michael Stevenson, President, Simon Frazer University

Dr. Suzanne Fortier, President NSERC

James Halliday, Master of Wine, Australia

John Salvi, Master of Wine, France

Dr. Linda Bisson, UC Davis

Dr. Sakkie Pretorius, VP Academic, Macquarie University, Australia

Dr. Dan Johnson, Director, Australian Wine Research Institute

Dr. Richard Gardener, University of Auckland, NZ

Dr. Terrance Cooper, University of Memphis

Dr. Mark Thomas, CSIRO-Adelaide, Australia

Dr. Reinhard Topfer, Geiweilerhof Siebeldingen, Germany

Dr. Keith Mitchelson, Australian Genome Research Facility (AGRF), Brisbane, Queensland, Australia

Dr. Charlie Boone, Banting and Best Institute, University of Toronto

Dr. Brenda Andrews, Banting and Best Institute, University of Toronto

Dr. Ritchie Younger, Facial Plastic Surgeon, Younger Facial Plastic Surgery Centre, Vancouver

Dr. Bruce Forster, Professor in the Department of Radiology, UBC and Head of MRI, Vancouver Coastal Region

Dr. Larry Stefan, President Stefan Frazer and Associates

Dr. Doyle Rogers, Physician, Entrepreneur, Monaco

Sid Cross, Lawyer and wine specialist

David Leslie, Australia

Dr. Steve Oliver, University of Manchester

Art Caputti, Director E&J Gallo

Philippe Bascaules, Head Wine Maker, Ch. Margaux

Ike Barber, Entrepreneur, Order of Canada and Order of British Columbia

Stu and Marilyn Blusson, Bbusinessman and Philanthropist

Anthony von Mandle, CEO Mark Anthony Group, Order of Canada and Order of British Columbia

Dr. Jay Keeling, UC Berkeley

Ken Cross, Entrepreneur

Haig Farris, Entrepreneur, President Fractal Capital, Order of Canada

Spud Matthews, Entrepreneur and Director

Canadian Government

The Hon. Bill Graham, Minister of Foreign Affairs and Minister of National Defence

The Hon. Michelle Rimple, Federal Member of Parliament

Senior executives at UBC

Dr. Stephen Toope

Dr. Arvind Gupta

Dr. John Hepburn

Dr. David Farrar

Dr. Don Brooks

Deans at UBC

Dr. Murray Isman, LFS

Dr. Dan Muzyka, Sauder School of Business

Dr. Michael Coughtrie, Pharmaceutical Sciences

Dr. John Innes, Forestry

Dr. Dermot Kelleher, Medicine